Bevacizumab (Anti-VEGF-A) Recombinant Antibody – Functional Grade

Price range: $600.00 through $15,000.00

Humanized monoclonal IgG1 antibody targeting VEGF-A (vascular endothelial growth factor A).

SKU: N/A Category:

Description

Bevacizumab is a humanized monoclonal IgG1 antibody that targets vascular endothelial growth factor A (VEGF-A), a key driver of angiogenesis. By binding VEGF-A and preventing its interaction with VEGF receptors, bevacizumab inhibits vascular development pathways and is widely used in studies of tumor biology and angiogenic signaling.

Additional information

Source

DrugBank DB00112

Buffer

PBS pH 7.4

Reactivity

Human

Immunogen

Recombinant human VEGF-A (vascular endothelial growth factor A)

Isotype

IgG1

Application

ELISA, WB

Heavy Chain Sequence

EVQLVESGGGLVQPGGSLRLSCAASGYTFTNYGMNWVRQAPGKGLEWVGWINTYTGEPTY
AADFKRRFTFSLDTSKSTAYLQMNSLRAEDTAVYYCAKYPHYYGSSHWYFDVWGQGTLVT
VSSASTKGPSVFPLAPSSKSTSGGTAALGCLVKDYFPEPVTVSWNSGALTSGVHTFPAVL
QSSGLYSLSSVVTVPSSSLGTQTYICNVNHKPSNTKVDKKVEPKSCDKTHTCPPCPAPEL
LGGPSVFLFPPKPKDTLMISRTPEVTCVVVDVSHEDPEVKFNWYVDGVEVHNAKTKPREE
QYNSTYRVVSVLTVLHQDWLNGKEYKCKVSNKALPAPIEKTISKAKGQPREPQVYTLPPS
REEMTKNQVSLTCLVKGFYPSDIAVEWESNGQPENNYKTTPPVLDSDGSFFLYSKLTVDK
SRWQQGNVFSCSVMHEALHNHYTQKSLSLSPGK

Light Chain Sequence

DIQMTQSPSSLSASVGDRVTITCSASQDISNYLNWYQQKPGKAPKVLIYFTSSLHSGVPS
RFSGSGSGTDFTLTISSLQPEDFATYYCQQYSTVPWTFGQGTKVEIKRTVAAPSVFIFPP
SDEQLKSGTASVVCLLNNFYPREAKVQWKVDNALQSGNSQESVTEQDSKDSTYSLSSTLT
LSKADYEKHKVYACEVTHQGLSSPVTKSFNRGEC

Format

Liquid

Endotoxins

Endotoxin Free

Notes

For research use only. Not suitable for clinical or therapeutic use.

Delivery Time

3-5 days if in stock; 3-5 weeks if out of stock

Stability and Storage

Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term. Avoid repeated freeze-thaw cycles.

Synonyms et alternative names

Anti-VEGF-A, anti-VEGF-A165, anti-VEGF, anti-vascular endothelial growth factor A

Reference Product

Avastin® (bevacizumab)

Avastin® is a registered trademark of Genentech, Inc. This product is not affiliated with, endorsed by, or manufactured by Genentech, Inc. or Roche.