Trastuzumab (Anti-HER2) Recombinant Antibody – Functional Grade

Price range: $600.00 through $15,000.00

Humanized monoclonal IgG1 antibody targeting HER2 (ERBB2)

SKU: N/A Category:

Description

Trastuzumab is a humanized monoclonal IgG1 antibody that targets the HER2 (ERBB2) receptor, which is overexpressed in certain cancer types. Binding to HER2 modulates receptor activity and downstream signaling pathways, making trastuzumab a commonly used reference antibody in oncology and receptor biology studies.

Additional information

Source

DrugBank DB00072

Buffer

PBS pH 7.4

Reactivity

Human

Immunogen

Recombinant human HER2 (ERBB2)

Isotype

IgG1

Application

ELISA, WB

Heavy Chain Sequence

EVQLVESGGGLVQPGGSLRLSCAASGFNIKDTYIHWVRQAPGKGLEWVARIYPTNGYTRY
ADSVKGRFTISADTSKNTAYLQMNSLRAEDTAVYYCSRWGGDGFYAMDYWGQGTLVTVSS
ASTKGPSVFPLAPSSKSTSGGTAALGCLVKDYFPEPVTVSWNSGALTSGVHTFPAVLQSS
GLYSLSSVVTVPSSSLGTQTYICNVNHKPSNTKVDKKVEPKSCDKTHTCPPCPAPELLGG
PSVFLFPPKPKDTLMISRTPEVTCVVVDVSHEDPEVKFNWYVDGVEVHNAKTKPREEQYN
STYRVVSVLTVLHQDWLNGKEYKCKVSNKALPAPIEKTISKAKGQPREPQVYTLPPSREE
MTKNQVSLTCLVKGFYPSDIAVEWESNGQPENNYKTTPPVLDSDGSFFLYSKLTVDKSRW
QQGNVFSCSVMHEALHNHYTQKSLSLSPGK

Light Chain Sequence

DIQMTQSPSSLSASVGDRVTITCRASQDVNTAVAWYQQKPGKAPKLLIYSASFLYSGVPS
RFSGSRSGTDFTLTISSLQPEDFATYYCQQHYTTPPTFGQGTKVEIKRTVAAPSVFIFPP
SDEQLKSGTASVVCLLNNFYPREAKVQWKVDNALQSGNSQESVTEQDSKDSTYSLSSTLT
LSKADYEKHKVYACEVTHQGLSSPVTKSFNRGEC

Format

Liquid

Endotoxins

Endotoxin Free

Notes

For research use only. Not suitable for clinical or therapeutic use.

Delivery Time

3-5 days if in stock; 3-5 weeks if out of stock

Stability and Storage

Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term. Avoid repeated freeze-thaw cycles.

Synonyms et alternative names

Anti-HER2, anti-ERBB2, anti-Human Epidermal Growth Factor Receptor 2

Reference Product

Herceptin® (trastuzumab)

Herceptin® is a registered trademark of Genentech, Inc. This product is not affiliated with, endorsed by, or manufactured by Genentech, Inc. or Roche.