Bispecific and Multispecific Antibodies

Bispecific and trispecific antibodies are gaining traction as revolutionary biologics to treat complex diseases.

Immune Biosolutions has successfully designed and produced several formats of multispecific antibodies and is looking forward to work with clients to push boundaries of bispecific and trispecific biologics.

Bispecific antibody pipelines

Knob-into-hole IgG (with common light chain)

Knob-into-hole is the most prevalent bispecific antibody format and has been a part of our pipeline.

2025 Figures BiSpecific 1

Antibody Fusion Protein

IgG protein

IgG-scFv

We have designed and generated a number of bispecific IgG-scFv. Our optimized constructs and pipeline are available for clients.

Antibody Formats 11 1

ScFv-scFv

Other formats of bispecific antibodies are also possible and could be optimized for clients.

scfv scfv

Trispecific antibodies

Immune Biosolutions has a solid design and production pipeline available to clients for multispecific antibodies.

IgG and IgG-scFv

Antibody Formats 12

Multiple scFv and monobodies

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tri knob into hole