SPR & BLI

Bio-Layer Interferometry (BLI) and Surface Plasmon Resonance (SPR) have become indispensable tools for screening protein–protein interactions across an ever-evolving range of antibody formats.

IgG

scFv

IgG-scFv

Nano-TCR

Custom antibody fusion proteins

Other custom requests

Formats

Kinetics

Binding Kinetics

Our team can perform and analyse high-resolution binding kinetic data and provide clients detailed reports including, but not restricted to the liste below:

  • Affinity – KD
  • Association Constant – Ka
  • Dissociation Constant – Kd

High-Throughput Screening

Pre-screening of a large number of clones can be challenging. We have successfully screened several large libraries to isolate binders and can develop custom pipelines on request.

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LT SPR binning

Binning

Antibody Binning

  • Sandwich assay
  • Premix assay
  • Tandem assay

Small and Large Molecules

Our Octet® RED384 system is designed to screen both small and large molecules

Small Molecules

Peptides

Nucleotides

Hormones

Haptens

Drugs

Large Molecules

Viral proteins

Large protein complexes

Lipoparticles

VLPs

Custom requests

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