Rituximab (Anti-CD20) Recombinant Antibody – Functional Grade

Price range: $600.00 through $15,000.00

Chimeric monoclonal IgG1 antibody targeting CD20 (MS4A1)

SKU: N/A Category:

Description

Rituximab is a chimeric monoclonal IgG1 antibody that recognizes the CD20 antigen (MS4A1) present on the surface of B cells. Binding to CD20 leads to B cell depletion via immune effector mechanisms and makes rituximab a widely utilized reagent in immunology and B cell-related research applications.

Additional information

Source

DrugBank DB00073

Buffer

PBS pH 7.4

Reactivity

Human

Immunogen

Recombinant human CD20 (MS4A1)

Isotype

IgG1

Application

ELISA, WB

Heavy Chain Sequence

QVQLQQPGAELVKPGASVKMSCKASGYTFTSYNMHWVKQTPGRGLEWIGAIYPGNGDTSY
NQKFKGKATLTADKSSSTAYMQLSSLTSEDSAVYYCARSTYYGGDWYFNVWGAGTTVTVS
AASTKGPSVFPLAPSSKSTSGGTAALGCLVKDYFPEPVTVSWNSGALTSGVHTFPAVLQS
SGLYSLSSVVTVPSSSLGTQTYICNVNHKPSNTKVDKKAEPKSCDKTHTCPPCPAPELLG
GPSVFLFPPKPKDTLMISRTPEVTCVVVDVSHEDPEVKFNWYVDGVEVHNAKTKPREEQY
NSTYRVVSVLTVLHQDWLNGKEYKCKVSNKALPAPIEKTISKAKGQPREPQVYTLPPSRD
ELTKNQVSLTCLVKGFYPSDIAVEWESNGQPENNYKTTPPVLDSDGSFFLYSKLTVDKSR
WQQGNVFSCSVMHEALHNHYTQKSLSLSPGK

Light Chain Sequence

QIVLSQSPAILSASPGEKVTMTCRASSSVSYIHWFQQKPGSSPKPWIYATSNLASGVPVR
FSGSGSGTSYSLTISRVEAEDAATYYCQQWTSNPPTFGGGTKLEIKRTVAAPSVFIFPPS
DEQLKSGTASVVCLLNNFYPREAKVQWKVDNALQSGNSQESVTEQDSKDSTYSLSSTLTL
SKADYEKHKVYACEVTHQGLSSPVTKSFNRGEC

Format

Liquid

Endotoxins

Endotoxin Free

Notes

For research use only. Not suitable for clinical or therapeutic use.

Delivery Time

3-5 days if in stock; 3-5 weeks if out of stock

Stability and Storage

Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term. Avoid repeated freeze-thaw cycles.

Synonyms and Alternative Names

Anti-CD20, anti-MS4A1, anti-B-lymphocyte antigen CD20

Reference Product

Rituxan® / MabThera® (rituximab)

Rituxan® is a registered trademark of Genentech, Inc. MabThera® is a registered trademark of Roche. This product is not affiliated with, endorsed by, or manufactured by Genentech, Roche, or Biogen.