Adalimumab (Anti-TNF-α) Recombinant Antibody – Functional Grade

Price range: $600.00 through $15,000.00

Fully human monoclonal IgG1 antibody targeting TNF-α (tumor necrosis factor alpha)

SKU: N/A Category:

Description

Adalimumab is a fully human monoclonal IgG1 antibody that specifically targets tumor necrosis factor alpha (TNF-α), a key mediator of inflammatory processes. Through high-affinity binding to TNF-α, adalimumab blocks cytokine interaction with its receptors and is frequently used in studies of immune regulation and chronic inflammation.

Additional information

Source

DrugBank DB00051

Buffer

PBS pH 7.5

Reactivity

Human

Immunogen

Recombinant human TNF-α (tumor necrosis factor alpha)

Isotype

IgG1

Application

ELISA, WB

Heavy Chain Sequence

EVQLVESGGGLVQPGRSLRLSCAASGFTFDDYAMHWVRQAPGKGLEWVSAITWNSGHIDY
ADSVEGRFTISRDNAKNSLYLQMNSLRAEDTAVYYCAKVSYLSTASSLDYWGQGTLVTVS
SASTKGPSVFPLAPSSKSTSGGTAALGCLVKDYFPEPVTVSWNSGALTSGVHTFPAVLQS
SGLYSLSSVVTVPSSSLGTQTYICNVNHKPSNTKVDKKVEPKSCDKTHTCPPCPAPELLG
GPSVFLFPPKPKDTLMISRTPEVTCVVVDVSHEDPEVKFNWYVDGVEVHNAKTKPREEQY
NSTYRVVSVLTVLHQDWLNGKEYKCKVSNKALPAPIEKTISKAKGQPREPQVYTLPPSRD
ELTKNQVSLTCLVKGFYPSDIAVEWESNGQPENNYKTTPPVLDSDGSFFLYSKLTVDKSR
WQQGNVFSCSVMHEALHNHYTQKSLSLSPGK

Light Chain Sequence

DIQMTQSPSSLSASVGDRVTITCRASQGIRNYLAWYQQKPGKAPKLLIYAASTLQSGVPS
RFSGSGSGTDFTLTISSLQPEDVATYYCQRYNRAPYTFGQGTKVEIKRTVAAPSVFIFPP
SDEQLKSGTASVVCLLNNFYPREAKVQWKVDNALQSGNSQESVTEQDSKDSTYSLSSTLT
LSKADYEKHKVYACEVTHQGLSSPVTKSFNRGEC

Format

Liquid

Endotoxins

Endotoxin Free

Notes

For research use only. Not suitable for clinical or therapeutic use.

Delivery Time

3-5 days if in stock; 3-5 weeks if out of stock

Stability and Storage

Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term. Avoid repeated freeze-thaw cycles.

Synonyms and Alternative Names

Anti-TNF-α, anti-TNF-alpha, anti-TNFA, anti-TNF-a, anti-TNF, anti-tumor necrosis factor alpha

Reference Product

Humira® (adalimumab, anti-TNFα)

Humira® is a registered trademark of AbbVie Inc. This product is not affiliated with, endorsed by, or manufactured by AbbVie Inc.