Chicken IgY Antibodies
Chicken IgY antibodies
Untapped, distinct and superior
Immune Biosolutions combines the considerable avian-mammalian phylogenetic distance with self-versus non-self-immune activation. Mammalian proteins are more immunogenic in chickens, and this results in better epitope coverage as well as increased antibody diversity and affinity. Mammalian IgG and avian IgY are both divalent and monomeric, and produced by analogous immune systems. Since, the variable regions of IgG and IgY are structurally similar, an IgY-derived single chain variable fragment (ScFv) can seamlessly undergo ultrahumanization, giving access to a novel therapeutic antibody repertoire.